Also known as: Idiopathic intracranial hypertension and Benign intracranial hypertension
- Birth control pills
- Sulfa drugs
- Nalidixic acid
- Steroids (starting or stopping them)
- Buzzing sound in the ears (tinnitus)
- Double vision (diplopia)
- Partial or permanent loss of vision. Patients often complain of blurred vision.
- Swelling of a small area in the back of the eye (papilledema)
- Increased head size
- Bulging anterior fontanelle in babies whose cranial sutures are not yet closed
- CT Scan
- Lumbar puncture (spinal tap)
- Eye exam, including formal visual field testing
- Fluid or salt restrictions
- Medications such as corticosteroids, glycerol, acetazolamide, and furosemide
- Shunting procedures to relieve pressure due to spinal fluid retention
- Surgery to relieve pressure on the optic nerve
- Weight loss
Pseudotumor cerebri is a process affecting the brain that appears to be -- but is not -- a tumor. It is often reversible.
Causes, incidence, and risk factors
The condition occurs more frequently in women than men, particularly in premenopausal obese women. It is rare in infants.
The cause is unknown. Certain medicines can increase your risk for this condition. These medicines include:
The following factors also associated with this condition:
The major symptom is increased pressure within the skull (increased intracranial pressure). There is no evidence of tumor, infection, blocked drainage of the fluid surrounding the brain, or any other cause.
Symptoms may get worse during physical activity, especially when tightening the stomach muscles.
Signs and tests
The doctor will perform a physical exam. Signs of this condition include:
Despite the increased pressure in the skull, there is no change in alertness.
Tests that may be done include:
The diagnosis is made when other health conditions are ruled out. Several conditions may cause increased intracranial pressure, including venous sinus thrombosis, hydrocephalus, and an intracranial mass (such as a tumor).
Treatment must be directed at the specific cause of the pseudotumor.
A lumbar puncture can help relieve pressure within the brain and prevent vision problems.
Other treatments may include:
The patient will need their vision closely monitored, since there is potential for progressive and sometimes permanent visual loss. Follow-up MRI or CT scans may be done to rule out hidden cancer.
Sometimes the condition disappears on its own within 6 months. About 10-20% of persons have their symptoms return. A small number of patients have symptoms that slowly get worse and lead to blindness.
Vision loss is a serious complication of this condition.
Calling your health care provider
Call your health care provider if you or your child experience the symptoms listed above.
Jonnalagadda J. Lithium, minocycline, and pseudotumor cerebri. J Am Acad Child Adolesc Psychiatry. March 1, 2005; 44(3): 209.
Behrman RE. Nelson Textbook of Pediatrics. 17th ed. Philadelphia, Pa: WB Saunders; 2004; 2048-2049.
- Review date:
- March 26, 2009
- Reviewed by:
- David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Daniel B. Hoch, PhD, MD, Assistant Professor of Neurology, Harvard Medical School, Department of Neurology, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
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