The Migraine and Pain Study (MAPS) GeneBank at Scripps Clinic Registry [STSI]

Inclusion Criteria:

• 1. Family members (genetic duo or trio), consisting of an adolescent 10 to 18 years of age and at least one of their biologic parents willing to be participate in trial
• 2. Adolescent and at least 1 biologic parent with Migraine diagnosis confirmed by Dr. Christy Jackson
• 3. Is reliable, cooperative and willing to comply with all protocol-specified procedures and/or sub-study if consented
• 4. Able to understand and grant informed consent

Exclusion Criteria:

• 1. Patient has been previously enrolled in the MAP GeneBank at Scripps Clinic Registry
• 2. Has a significant chronic medical condition (i.e.chronic meningitis or a secondary origin/cause of headache) which, in the investigator's option, may interfere with the patient's optimal participation in the study
• 3. Treatment with any investigational agents or devices within 30 days preceding enrollment in the study
• 4. Has undergone ECT within 90 days preceding enrollment in the study