Clinical Research

Shiley Center for Orthopaedic Research and Education

Shiley Center for Orthopaedic Research and Education (SCORE) at Scripps Clinic in San Diego, Calif. brings findings from the lab to the patient’s bedside through its clinical research programs. By conducting privately and publically sponsored clinical trials, SCORE allows consumers to gain access to investigational drugs and devices before they are approved for the marketplace. The center’s clinical research interests include the following:

Blood clot prevention

Our clinicians and scientists study alternatives to traditional anticoagulation therapy, such as portable calf compression devices (CECT) and experimental medications.

Hip and knee implants

We test whether experimental and FDA-approved implants provide enhanced function of the joint, better quality of life for the patient and improved wear rates.

Pain management

Focusing on conventional and complementary approaches, our nurses and physicians investigate new medications, processes and therapies to alleviate pain after orthopedic surgery.

Physical rehabilitation

Using information from an electronic knee prosthesis pioneered and developed by SCORE that measures forces in the joint, physical therapists are working to develop safer and more effective rehabilitation programs and activity recommendations for people who have undergone total knee replacement surgery.

Genomics

SCORE is trying to identify the genes linked to osteoarthritis, the most common form of arthritis. The findings may one day lead to earlier diagnosis and the development of new therapies that can be applied at a younger age, reducing the need for surgical intervention.

For more information about SCORE’s current clinical research activities, call 858-332-0123