Articles

  • Disease

    Thalassemia

    Thalassemia major is an inherited form of hemolytic anemia, characterized by red blood cell (hemoglobin) production abnormalities. This is the most severe form of anemia, and the oxygen depletion in the body becomes apparent within the first 6 months of life. If left untreated, death usually results within a few years. Note the small, pale (hypochromic), abnormally-shaped red blood cells associated with thalassemia major. The darker cells likely represent normal RBCs from a blood transfusion.

    Thalassemia is a blood disorder passed down through families (inherited) in which the body makes an abnormal form of , the protein in red blood cells that carries oxygen. The disorder results in excessive destruction of red blood cells, which leads to anemia. See also:

  • Disease

    Thrombocytopenia

    Thrombocytopenia is any disorder in which there is an abnormally low amount of platelets. Platelets are parts of the blood that help blood to clot. This condition is sometimes associated with abnormal bleeding.

  • Special Topic

    Thrombolytic therapy

    Thrombolytic therapy is the use of drugs to break up or dissolve blood clots, which are the main cause of both heart attacks and stroke.

  • Disease

    Thrombotic thrombocytopenic purpura

    Blood is comprised of red blood cells, platelets, and various white blood cells.

    Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that causes blood clots to form in small blood vessels around the body, and leads to a low platelet count (). See also:

  • Test

    Total iron binding capacity

    Blood is drawn from a vein (venipuncture), usually from the inside of the elbow or the back of the hand. A needle is inserted into the vein, and the blood is collected in an air-tight vial or a syringe. Preparation may vary depending on the specific test.

    Total iron binding capacity (TIBC) is a blood test to see if you may have too much or too little iron in the blood. Iron moves through the blood attached to a protein called transferrin. This test helps your doctor know how well that protein can carry iron in the blood.

  • Disease

    Transfusion reaction - hemolytic

    A complication of blood transfusion where there is an immune response against the transfused blood cells.

    A hemolytic transfusion reaction is a serious problem that occurs after a patient receives a transfusion of blood. The red blood cells that were given to the patient are destroyed by the patient’s immune system. There are other types of allergic transfusion reactions that do not cause .