Also known as: Amyloidosis - hereditary and Familial amyloidosis
- Senile systemic: seen in people older than 70
- Spontaneous: occurs without a known cause
- Secondary: results from diseases such as cancer of the blood cells (myeloma)
Hereditary amyloidosis is a condition in which abnormal protein deposits (called amyloid) form in almost every tissue in the body. Deposits most often form in the heart, kidneys, and nervous system. These protein deposits damage the tissues and interfere with how organs work.
Hereditary amyloidosis is passed down from parents to their children (inherited). Genes may also play a role in primary amyloidosis.
Other types of amyloidosis are not inherited. They include:
Specific conditions include:
A liver transplant may be helpful. Talk to your health care provider about treatments.
Ferri FF. Amyloidosis. In: Ferri FF, ed. Ferri's Clinical Advisor 2016. Philadelphia, PA: Elsevier Mosby; 2016:e2-105.e5.
Gertz MA. Amyloidosis. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 25th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 188.
Seldin DC, Skinner M. Amyloidosis. In: Firestein GS, Budd RC, Gabriel SE, McInnes IB, O'Dell JR, eds. Kelley's Textbook of Rheumatology. 9th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 116.
- Review date:
- December 07, 2016
- Reviewed by:
- Chad Haldeman-Englert, MD, FACMG, Fullerton Genetics Center, Asheville, NC. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
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