Investigational Drug for to treat Metastatic Pancreatic Ductal Adenocarcinom

Trial ID:
Darren Sigal, M.D.
This is a double blind, phase 3 trial to evaluate the effectiveness of the Investigational Drug PEGPH20 compared to placebo when given in combination with standard chemotherapy (Abraxane + Gemzar). Treatment will continue until disease progression, unacceptable toxicity, or withdrawal of consent.

Inclusion Criteria

  • Be over the age of 18 with a life expectancy of over 3 months
  • Have stage IV pancreatic ductal adenocarcinoma
  • Have at least 1 tumor metastasis measurable by CT

Exclusion Criteria

  • Have had previous radiotherapy, surgery, chemotherapy, or investigative therapy for the treatment of metastatic disease
  • Have a history of stroke or transient ischemic attack
  • Have metastases to the brain

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