Inclusion Criteria

• Have been diagnosed with MacTel Type 2
• Be at least 21 but less than 80 years of age
• Have visual acuity of at least 20/80 in one eye

Exclusion Criteria

• Have had anti-angiogenic injections (such as Avastin) in either eye
• Have other eye diseases (mild diabetic changes may be acceptable)
• Have other health conditions that would prevent having a surgical procedure
• Be pregnant or nursing
• Be HIV positive

Additional Info

• The NT-501 is a very small device (about the size of a grain of rice) that is implanted in the back of the eye and releases a protein that may protect the eye from further damage. Previous studies show that the NT-501 device may slow the progression of MacTel Type 2.
• The NT-501 device will be compared to a sham/placebo; nothing will be placed in the eye during the Sham procedure.
• This study is randomized which means there is a 50/50 chance of receiving the implant or the Sham/placebo procedure.