New investigational implant for MacTel Type 2

Trial ID:
IRB-17-7052
Richard Lin, MD
There is currently no treatment for MacTel Type 2. The goal of this study is to evaluate the safety and effectiveness of an investigational implant, NT-501, to slow the progression of the disease. <br><br>This is a 2 year study that requires 9 visits. <br>

Inclusion Criteria

  • Have been diagnosed with MacTel Type 2
  • Be at least 21 but less than 80 years of age
  • Have visual acuity of at least 20/80 in one eye

Exclusion Criteria

  • Have had anti-angiogenic injections (such as Avastin) in either eye
  • Have other eye diseases (mild diabetic changes may be acceptable)
  • Have other health conditions that would prevent having a surgical procedure
  • Be pregnant or nursing
  • Be HIV positive

Additional Info

  • The NT-501 is a very small device (about the size of a grain of rice) that is implanted in the back of the eye and releases a protein that may protect the eye from further damage. Previous studies show that the NT-501 device may slow the progression of MacTel Type 2.
  • The NT-501 device will be compared to a sham/placebo; nothing will be placed in the eye during the Sham procedure.
  • This study is randomized which means there is a 50/50 chance of receiving the implant or the Sham/placebo procedure.

Contact Info:

  • Shannon Cyhan
  • cyhan.shannon@scrippshealth.org