Trials

Showing 1-10 trials of 198 total

• Cardiology and Vascular Diseases

  The Genebank at Scripps Clinic Registry

  This trial is not currently enrolling

  This proposal puts forward a research plan to initiate a genetic databank, henceforth referred to as The Genebank at Scripps Clinic Registry. This database will usher in genomic research at Scripps as we strive to stay at the forefront of cardiovascular research in the new century. Human subject ...

• Genetics|Genomics|Healthy Donors

  Study of the Genetics of Healthy Aging

  This trial is currently enrolling

  This study will work towards identifying the genetic factors responsible for maintaining health. The study is looking at the DNA of individuals who have lived over 80 years and have not experienced a chronic illness or disease. Participantion requires one visit and includes a small blood sample.

• Substance Abuse and Addictions

  Medication Development for Protracted Abstinence in Alcoholism: Naltrexone Versus Acamprosate

  This trial is not currently enrolling

  The purpose of this study is to develop and validate a human laboratory model for prediction of medication efficacy in clinical trials for relapse prevention in alcohol dependence. This study involves two laboratory sessions and an fMRI scan.

• Substance Abuse and Addictions

  New investigational drugs for alcohol dependence

  This trial is currently enrolling

  A 12-week study will be conducted with 150 outpatients with alcohol dependence, with random assignment to pregabalin 300 mg/day, duloxetine 40 mg/day, or placebo in conjuction with behavioral counseling and follow-up visits 1 week and 3 months post-treatment. Requires 2 screening visits. Weekly ...

• Genomics

  A randomized, placebo-controlled trial of pioglitazone, compared with placebo, for prevention of stroke and myocardial infarction after ischemic stroke and transient ischemic attack

  This trial is not currently enrolling

  The purpose of this study is to determine if pioglitazone is effective in preventing future strokes or heart attacks among non-diabetic persons who have had a recent ischemic stroke.

• Genetics

  The Migraine and Pain Study (MAPS) GeneBank at Scripps Clinic Registry [STSI]

  This trial is not currently enrolling

  The objective of this study is to obtain blood or saliva samples to define genes for migraine and pain diseases.

• Cancer

  Scripps Polster Breast Care Center InvestigatioNal GenebanK (PINK)

  This trial is not currently enrolling

  Breast cancer is a disease of complex origin with a strong genetic component. The incidence of breast cancer is very high in monozygotic twins of patients, and it is thought that a high proportion and perhaps the majority of breast cancers arise in a small number of genetically susceptible women. ...

• Allergy, Asthma, Immunology

  Aspirin Desensitization in aspirin-exacerbated respiratory disease

  This trial is currently enrolling

  This study evaluates new methods of desensitizing patients to aspirin. It requires 2-3 full days in an outpatient clinic.

• Genomics

  Genetic Investigation of Solid Tumors (GIST) Cohort

  This trial is not currently enrolling

  The objective of this study is to obtain blood samples, solid tumor and/or benign hyperplasia samples to learn more about genetic differences that are linked to the formation of solid tumors.

• Orthopedics

  Osteocel Plus in Anterior Cervical Discectomy and Fusion (ACDF): Evaluation of Radiographic and Patient Outcomes [Protocol: NUVA.OC - 0802]

  This trial is not currently enrolling

  This is a prospective, non-randomized multi-center study to compare the use of Osteocel Plus in subjects who receive ACDF surgery at one or two levels. These subjects will present with degenerative conditions in the cervical spine that are amenable to surgical treatment and will be screened prior ...