Active Studies

Showing 31-40 trials of 199 total

• Cancer

  A Multi-center, Phase 2, Single-Arm, Open-Label Exploratory Study of Individually-Optimized Conditioning Using Pharmacokinetics [PK]-directed Dose Adjustment of Once Daily Intravenous Busulfan, Followed by Autologous Hematopoietic Stem Cell Transplant in Subjects with Non-Hodgkin’s Lymphoma and Hodgkin’s Lymphoma, Otsuka Protocol No. 273-08-201

  This trial is not currently enrolling

  This is a study for the outcome and safety of individualized busulfan dosing with cyclophosphamide and etoposide for patients preparing for a stem cell transplant to treat Non-Hodgkin or Hodgkin’s Lymphoma.

• Genetics

  Metabolomics of Aging: A Sub-Study of the Healthy Elderly Active Longevity (HEAL) Cohort

  This trial is currently enrolling

  This research is being done to learn more about healthy aging. We hope to learn which bodily processes or functions are important for the elderly to maintain good health. Metabolites (for example, glucose) are small molecules in our bodies that are used in all bodily reactions. Looking at their ...

• A N-of-1 Hypertensive Ambulatory Trial

  This trial is currently enrolling

  The purpose of this trial is to evaluate if an objective clinical decision of anti-hypertensive therapy can be made using an N-of-1 (single patient) trial design.

• A Randomized, Open-Label Phase IIb Trial of Maintenance Therapy with a MUC1 Dendritic Cell Vaccine (CVacTM) for Epithelial Ovarian Cancer Patients in First or Second Remission [Protocol:CAN-003]

  This trial is not currently enrolling

  The purpose of this study is to determine the safety and efficacy of an investigational therapeutic agent (Cvac)in ovarian cancer patients in first or second remission and to determine its ability to prevent cancer from returning.

• Cancer

  A Randomized Phase III Study of Elacytarabine vs. Investigator’s Choice in Patients with Late Stage Acute Myeloid Leukemia [Protocol: CP4055-306]

  This trial is not currently enrolling

  The purpose of the study is to assess the efficacy and safety of elacytarabine versus investigator’s choice treatment in patients with relapsed or refractory acute myeloid leukemia (AML).

• Transplant - Organ and Tissue

  Discovery and Validation of Proteogenomic Biomarker Panels in a Prospective Serial Blood & Urine Monitoring Study of Kidney Transplant Recipients - Transplant Proteogenomics [CTOT]

  This trial is currently enrolling

  There is a need to develop blood and/or urine tests that will help to detect early signs of rejection in people who have had kidney transplant. Researchers will examine blood, urine, and tissue samples and try to identify genetic markers for certain conditions like rejection, response to therapy, ...

• Placement of AoRTic TraNscathetER Valves Trial (The PARTNER II Trial) - The Safety and Effectiveness of the SAPIEN XT™ Transcatheter Heart Valve with NovaFlex and Ascendra/Ascendra 2 delivery systems(transfemoral and transapical)in Intermediate and High Risk for Aortic Valve Surgery and Patients Who Cannot Undergo Surgery [2010-12-US]

  This trial is currently enrolling

  The purpose of this trial is to determine the safety and effectiveness of the Edwards SAPIEN XT transcatheter heart valve and delivery systems: NovaFlex (transfemoral access) and Ascendra2 (transapical access) in patients with symptomatic, calcific, severe aortic stenosis.

• Pulmonary Medicine

  A Phase III international, randomized, double-blind, double-dummy study to evaluate the efficacy and safety of 300 mg or 600 mg of intravenous zanamivir twice daily compared to 75 mg of oral oseltamivir twice daily in the treatment of hospitalized adults and adolescents with influenza (Protocol NAI114373)

  This trial is currently enrolling

  The purpose of this study is to test the safety and efficacy of zanamivir given intravenously and how well it works at two different doses in hospitalized adolescents and adults with flu. Zanamivir will be compared with oseltamivir, which is used for treating flu.

• Cardiology and Vascular Diseases

  A Prospective Evaluation in a Randomized Trial of the Safety and Efficacy of the Use of the TAXUS® Element™ Paclitaxel-Eluting Coronary Stent System for the Treatment of De Novo Coronary Artery Lesions (PERSEUS)

  This trial is not currently enrolling

  This study is to compare the safety and performance of two stents coated with the same drug (the TAXUS Element Paclitaxel-Eluting Coronary Stent System and the TAXUS Express2 Paclitaxel-Eluting Coronary Stent System).

• Cancer

  Nonmyeloablative Allogeneic Stem Cell Transplantation for Patients using Antithymocyte Globulin and with Cladribine-Melphalan or Total Lymphoid Irradiation

  This trial is currently enrolling

  Allogeneic transplant from a matched sibling for the treatment of a variety of illnesses including bone marrow failure states, leukemias, myelodysplastic or myeloproliferative syndromes, lymphoma, or myeloma using a nonmyeloablative preparative regimen.