In this single center, randomized, placebo-controlled clinical trial, adults diagnosed with Episodic Migraine and Irritable Bowel Syndrome will be randomly chosen to receive a once daily, commercially-available probiotic supplement or a placebo for 12-weeks. Two clinic visits and two brief telephone calls with the research coordinator are required over 16-weeks.
Be 18-75 years of age.
Have Episodic Migraines (3-12 migraines per month).
Be diagnosed with Irritable Bowel Syndrome.
Have been on a steady treatment regimen for at least 6-months.
Be willing to attend 2 in-person visits to Scripps Clinic.
Have access to a smartphone or computer to complete surveys.
Patients must not:
Currently take probiotic supplements.
Have taken antibiotics in the previous 3-months.
Have other gastrointestinal or hepatic diagnoses (e.g., SIBO, IBD).