Agenda IBD Cutting Edge 2025: Where Innovation, Trials, and Multidisciplinary Care Intersect

Drug Development in 2025: Setting the Stage

9:30 a.m.                           

Registration, Refreshments & View Exhibits

10:30 a.m.         

Welcome & Educational Overview

Amy Lightner, MD – Scripps Clinic San Diego

How Translational Science is Relevant to the Clinic

Moderators: Marla Dubinsky, MD and Howard Hang, PhD

10:40 a.m.         

Developing New Drug Targets: Considerations and Pre-clinical Logistics

Arnab Chatterjee, PhD – Scripps Research San Diego

10:55 a.m.         

Regenerative Medicine Beyond Cell Therapy: How We Might Break the Therapeutic Ceiling

Michael Bollong, PhD – Scripps Research San Diego

11:10 a.m.         

Biological Drivers of Response to Therapies

Maria Abreu, MD – Cedars-Sinai Medical Center Los Angeles

11:25 a.m.         

Targeting Regulatory T-Cells in IBD

Scott Snapper, MD, PhD – Boston Children’s Hospital

11:40 a.m.        

The Role of Artificial Intelligence in Drug Discovery

Pradipta Ghosh, MD - University of California San Diego

Noon                 

Panel Discussion/Q&A

12:20 p.m.         

Drug Development in 2025: Challenges and Solutions in Maximizing the Intersection Between Academia and Industry

Peter Schultz, PhD – Scripps Research San Diego

1 p.m.                 

Lunch

Controversies in Clinical Trials: The GI’s Perspective

Moderators: Siddharth Singh, MD and Maria Abreu, MD

2 p.m.                 

PROs as Endpoints

Marla Dubinsky, MD – Mount Sinai New York

2:15 p.m.                           

Intestinal Ultrasound as a Treat to Target Endpoint

Gauree G. Konijeti, MD, MPH – Scripps Clinic San Diego

2:30 p.m.            

Advanced Therapies in Phase 2 and Phase 3 - Which Trials to Participate in and the Biggest Challenges with Patient Recruitment

James Marion, MD – Mount Sinai New York

2:45 p.m.            

Considerations of Mild-to-Moderate UC and Crohn’s Phenotypes in Drug Development

Alan Moss, MD – Boston University

3 p.m.  

Rethinking Clinical Trial Design

David Rubin, MD – University of Chicago

3:15 p.m.          

Panel Discussion/Q&A

3:30 p.m.            

Break & View Exhibits

Controversies in Clinical Trials: The Surgical Perspective

Moderators: Paulo Kotze, MD, PhD and Tracy Hull, MD

4 p.m.  

Surgical Technique Decreasing Postoperative Recurrence – Close the Door or Expand On What’s Been Done?

Andre D’Hoore, MD, PhD – IBD Leuven Belgium

4:15 p.m.                           

Scoring Endoscopic Recurrence After Ileocecal Resection for Clinical Trials: A Martial Art?

Willem Bemelman MD PhD, Amsterdam, Netherlands

4:30 p.m.                           

Your Ulcerative Colitis Operation Could be Preventative – Do an Appendectomy!

Janindra Warusavitarne, B Med, FRACS, PhD - St. Mark’s Hospital London

4:45 p.m.                           

Top Three Surgical Trials Still to be Done

Phillip Fleshner MD – Cedars Sinai, Los Angeles, CA

5 p.m.                 

Panel Discussion/Q&A

5:30 p.m.                           

Adjourn 

Implementing New Technology and Drug Discovery into Clinical Practice

Moderators: James Marion, MD and Janindra Warusavitarne, B Med, FRACS, PhD

7 a.m.                 

Breakfast & View Exhibits

7:55 a.m.                           

Welcome & Announcements

Gauree G. Konijeti, MD, MPH – Scripps Clinic San Diego

Coffee & Debates

8 a.m.  

Colectomy or Not with High Grade Dysplasia

PRO: Tracy Hull, MD - Cleveland Clinic

CON: David Rubin, MD – University of Chicago

8:30 a.m.            

Crohn’s and Indeterminate Colitis – To Pouch or Not to Pouch

PRO: Phillip Fleshner, MD - Cedars-Sinai Medical Center Los Angeles

CON: Marla Dubinsky, MD - Mount Sinai New York

Applying Clinical Trials in GI and Surgery

Moderators: Willem Bemelman, MD, PhD and David Rubin, MD

9 a.m.                 

Evolving Demographics of the IBD Patient Population: How Do We Address It?

Alan Moss, MD – Boston University

9:15 a.m.                           

Applying Clinical Trial Results to the Pediatric Population

Jeannie Huang, MD – Rady Children’s Hospital San Diego

9:30 a.m.            

Rethinking Early Surgery in Crohn’s

Paulo Kotze, MD, PhD – Catholic University of Parana Curitaba, Brazil

9:45 a.m.                           

What the Data Shows About Using Two Advanced Therapies at the Same Time

Maria Abreu, MD – Cedars-Sinai Medical Center

10 a.m.

Applying Clinical Trial Results to Pouches

Edward Barnes, MD – UNC School of Medicine

10:15 a.m.         

Panel Discussion/Q&A

10:30 a.m.         

Break & View Exhibits

Choosing Among the Plethora of Medical Therapies

Moderators: Maria Abreu, MD and David Schwartz, MD

10:45 a.m.         

Subcutaneous Infliximab and Vedolizumab

Mazer Ally, MD – Scripps Clinic San Diego

11 a.m.               

Anti-IL23 Therapies

Edward Barnes, MD – UNC School of Medicine

11:15 a.m.         

S1P Inhibitors

Gauree G. Konijeti, MD, MPH – Scripps Clinic San Diego

11:30 a.m.         

JAK Inhibitors

Brigid Boland, MD - University of California San Diego

11:45 a.m.         

Positioning Therapies in Crohn’s Disease

Siddharth Singh, MD – Mayo Clinic Arizona

Noon    

Positioning Therapies for Ulcerative Colitis

David Rubin, MD – University of Chicago

12:15 p.m.         

Panel Discussion/Q&A

12:30 p.m.         

Lunch Symposium

Non-CME Activity Hosted by AbbVie

Bringing it All Together – What We Do Best! Clinical Cases with Your Multidisciplinary Team

Moderators: Willem Bemelmen, MD, PhD and James Marion, MD

1:30 p.m.                           

Medical Management of Acute Severe UC: What to Rule Out, What are Your Medications, and What to Watch Out For

Marla Dubinsky, MD - Mount Sinai New York

1:45 p.m.                           

Update in Surgical Approach to Ulcerative Colitis

Andre D’Hoore MD, PhD – IBD Leuven Belgium

2 p.m.                 

The Importance of the Patient Voice in Considering Outcome Measures

Tina Aswani-Omprakash, MPH - South Asian IBD Alliance

2:15 p.m.                           

Case 1: Acute-Severe UC

Panel: Marla Dubinsky, BA, PhD, Andre D’Hoore, MD, PhD, Alan Moss, MD, and Valery Vilchez, MD

2:45 p.m.                           

Break & View Exhibits

Moderators: Tracy Hull, MD and Gauree G. Konijeti, MD, MPH

3:15 p.m.                           

Perianal Crohn’s Disease Activity Index and MRI – More than Measurements

Phil Tozer, MBBS – St. Mark’s Hospital London

3:30 p.m.            

Optimizing the Medical Management of Perianal Fistula

David Schwartz, MD – Vanderbilt University

3:45 p.m.            

Does Diversion Have a Role in the Management of Perianal Disease?

Phillip Fleshner, MD - Cedars-Sinai Medical Center Los Angeles

4 p.m.                 

ADMIRE 2 was a Negative Trial: Are MSCs Still an Option or is Something New on the Horizon?

Amy Lightner, MD – Scripps Clinic San Diego

4:15 p.m.                           

Case 2: Refractory Perianal Fistulizing Disease

Panel: Mazer Ally, MD, Andre D’Hoore, MD, PhD, David Schwartz, MD, and Phil Tozer, MD

4:45 p.m.                           

Adjourn

5 p.m.                 

Welcome Reception

Non-CME Activity Hosted by Takeda

Managing IBD in Clinical Practice

7 a.m.                 

Breakfast & View Exhibits

7: 55 a.m.           

Welcome & Announcements

Siddharth Singh, MD – Mayo Clinic Arizona

Managing Diet and Therapy in Specific Situations

Moderators: Gauree G. Konijeti, MD, MPH and Paulo Kotze, MD, PhD

8 a.m.                 

Use of Diet and Supplements in IBD

Lori Beeken, MS, RDN – Scripps Clinic San Diego

8:15 a.m.                           

Endoscopic Therapies for Stricturing Crohn’s Disease

Mazer Ally, MD – Scripps Clinic San Diego

8:30 a.m.                           

Perioperative Management of IBD Therapies

Amy Lightner, MD – Scripps Clinic San Diego

8:45 a.m.                           

Postoperative Prophylaxis in Crohn’s Disease – Keeping the Surgeon Away!

Preetika Sinh, MD – University of California San Diego

Day-to-Day Realities of Clinical Practice

Moderators: Siddharth Singh, MD and Janindra Warusavitarne, B Med, FRACS, PhD

9 a.m.                 

Health Maintenance in IBD

Gil Melmed, MD – Cedars-Sinai Medical Center

9:15 a.m.                           

IBD and Pregnancy

Brigid Boland, MD - University of California San Diego

9:30 a.m.                           

Update in the Management of Pediatric IBD

Jeannie Huang, MD – Rady Children’s Hospital San Diego

9:45 a.m.                           

Dermatology & IBD

Charisse Orme, MD, PhD – University of California San Diego

10 a.m.               

Panel Discussion/Q&A

10:30 a.m.         

Main Conference Adjourns

*Topics, times and speakers are subject to change

10:30 a.m.                 

Break for APP Track Attendees

10:40 a.m.                 

Welcome & Educational Overview

10:45 a.m.                 

APP Digest: Medications 

Angelina Collins, MSN, ANP-BC – University of California San Diego

11 a.m.                       

APP Digest: Special Populations

Melissa Ferrari, PA-C – Scripps Clinic San Diego

11:15 a.m.                 

APP Digest: Surgery

Karrie Driscoll, MSN, ANP-BC – University of California San Diego

11:30 a.m.                 

Panel Discussion/Q&A

11:45 a.m.                 

Advanced Practice Provider Track Adjourns