Invasive nerve ablation procedure for relief of heart failure symptoms.
- Trial ID:
- IRB-21-7827
- Rajeev Mohan, MD
Inclusion Criteria
Patients must:- Be 40 years of age or older
- Have chronic heart failure diagnosis
- Be currently taking treatment with oral diuretic for 30 days or more
- Have an LVEF = 50 % determined by echocardiogram within the past 6 months.
Exclusion Criteria
Patients must not:- Have a BMI > 45 kg/m2
- Have a history of clinically significant liver cirrhosis
- Be dialysis dependent
- Have chronic pulmonary disease requiring continuous home oxygen.
- Be unable to walk less than 100 meters OR a distance greater than 450 meters in six minutes.
Additional Info
- Eligible participants will be randomized to either ablation using the Axon System (treatment cohort) or a sham procedure (control cohort). Participants will have post-procedure follow-up visits at 7 days, and 1, 3, 6 and 12-months.
Contact Info:
- CRS Leadership
- CRSLeadership@scrippshealth.org