New Investigation Treatment for Heart Failure w/Reduced Ejection Fraction HFrEF1

Trial ID:
IRB-23-8167
Thomas Heywood, M.D.

Inclusion Criteria

Patients must:

  • Be between 18 and 80 years of age
    Be diagnosed with heart failure for at least 60 days
    Have an ejection fraction less than or equal to 35%
    Have an implantable cardioverter-defibrillator (ICD)
    Be NYHA Class III meaning symptoms while performing some activities of daily living but are comfortable

Exclusion Criteria

Patients must not:

  • Have a new diagnosis of heart failure previously untreated.
    Have had Cardiac surgery, percutaneous coronary intervention (PCI), valvuloplasty or valve replacement within 90 days prior to screening.
    Have a diagnosis of, or treatment for, any cancer within the last 5 years except for Grade 1 prostate cancer, basal cell carcinoma or carcinomas in situ where surgical excision was considered curative.

Additional Info

*The treatment involves a one-time infusion in your coronary arteries. This involves undergoing cardiac catheterization.

*There will be 11 visits over approx. 1 year with reimbursement for travel expenses

*Biannual telephone calls will occur to check on your health status for 4 additional years

* Visits include physical examination, lab tests, echocardiogram, 6-minute walk test, and ICD
interrogation.

Contact Info:

  • Clinical Research Services
  • CRSleadership@Scrippshealth.org