Nociscan MR Spectroscopy scan in patients for Degenerative Low Back Pain

Trial ID:
IRB-25-8533
Hani Malone, MD

Inclusion Criteria

Patients must:

  • Be 18 to 70 years of age.
  • Be planning to undergo surgical treatment of degenerative lumbar disc (discogenic) back pain.
  • Have a diagnosis of damaged or disease lumbar disc (discogenic) back pain that requires treatment in the lumbar spine caused by degenerative disc disease (identified via MRI).
  • Have failed at least 6 months of non-operative treatment (for example: physical therapy, bed rest, chiropractic care, acupuncture, massage therapy) OR requires urgent surgical treatment.

Exclusion Criteria

Patients must not:

  • Have a primary diagnosis of a spinal condition other than degenerative disc disease.
  • Have had prior lumbar back surgery or intradiscal treatments.
  • Have severe spinal canal stenosis.
  • Be pregnant or breast feeding when scans are performed.
  • Have a BMI greater than 40.
  • Be currently receiving worker's compensation, involved in any litigation for personal injury, medical negligence, trauma or worker's compensation.

Additional Info

Patients will be randomized (like the flip of a coin) to 1 of 2 groups: Unblinded and Blinded NOCISCAN reports.

Magnetic Resonance Spectroscopy (MRS) Scan will take place at Scripps Green Hospital Torrey Pines.

Study participation will consist of 4 follow-up visits after Magnetic Resonance Spectroscopy (MRS) scan. Total study duration is expected to be up to 24 months.

For more information on the study search NCT06661850 at www.ClinicalTrials.gov

Contact Info:

  • Clinical Research Services
  • CRSLeadership@scrippshealth.org