What Does an Abnormal Mammogram Mean?
Early detection and advanced treatment options help save lives

Louis Rivera, MD, Surgical Oncologist, Scripps Clinic.
Early detection and advanced treatment options help save lives
There’s no question that mammograms save lives. According to the American Cancer Society, since 1989 more than 500,000 breast cancer deaths in the US have been prevented thanks to early detection and advanced treatment options.
“Fortunately for the majority of women who have breast cancer in the modern era, the potential for survival after the diagnosis well exceeds 85 to 90 percent,” says Louis Rivera, MD, a surgical oncologist at Scripps Cancer Center and Scripps Clinic. “A lot of that is attributable to screening mammography because the cancer is detected early at a stage where it can be readily treated.”
Still, for those who hear those fateful words, it can feel like the start of a journey into the unknown. Here, Dr. Rivera walks us through each step, from diagnostics to recovery.
What is a diagnostic mammogram?
Whether an abnormality is found during a routine mammogram or a self-exam, the first step is a diagnostic mammogram, where specialized images that allow for greater magnification are captured. A diagnostic mammogram often includes an ultrasound of the area.
“Many people are familiar with sonography during pregnancy,” says Dr. Rivera; “the exact same instrumentation is used to create a picture of the breast.”
A diagnostic mammogram allows radiologists to further characterize the abnormality and determine what would be the best approach for biopsy, if they determine that’s needed.
If so, they take a sample using a hollow needle guided by ultrasound or stereotactic guidance, in which radiologists use the same setup as the mammogram. The sample is then sent to a lab.
What is multidisciplinary care?
Once cancer is detected, multidisciplinary care comes into play.
Doctors work together to determine the best course of action based on the stage of the cancer, how aggressive it seems to be and whether the cells contain hormone receptors that cause tumor growth when stimulated and can be targeted with drugs to reduce the tumor’s size.
Some patients benefit from chemotherapy first. Others may benefit from surgery.
Lumpectomy vs mastectomy
There are two types of surgery: breast conserving surgery, often called a lumpectomy, and mastectomy, or breast removal. A lumpectomy is the most common. Surgeons remove the tumor, a small amount of surrounding tissue and sometimes nearby lymph nodes. Lumpectomies can usually be done as outpatient surgery and rarely require any post-op pain medicine stronger than ibuprofen or acetaminophen.
“Overall, the recovery is measured in days to maybe a week or two,” says Dr. Rivera. By comparison, recovery from a mastectomy range from a few weeks to two months.
For larger or multiple tumors, and in certain other situations, a mastectomy may be the most beneficial. During a mastectomy, the surgeon removes all breast tissue and sometimes the nipple and breast skin. Both lumpectomies and mastectomies change the appearance of the breast, but restoration is often possible with the help of plastic surgery.
What does radiation therapy do?
Some patients are referred for radiation therapy. “Most patients who get breast conserving surgery will benefit from the addition of radiation therapy to prevent the cancer from coming back,” says Dr. Rivera.
“Most patients who get breast removal don't require radiation, unless there’s something concerning about their cancer, large tumors, involvement of skin or the chest, or the presence of cancer in their lymph nodes. That's a bit of an advantage over lumpectomy.”
Can breast cancer return?
Breast cancer patients are monitored frequently following treatment. The highest risk of recurrence is within the first three years, but Dr. Rivera and the rest of the Scripps oncology team actively monitor patients for the first five years, sometimes longer, depending on their stage of disease.
Dr. Rivera stresses that once there's no longer evidence of disease, most patients will remain cancer free for the rest of their lives. However, breast cancer can return in a much more delayed fashion, 10 to 20 years later, so patients are asked to be vigilant for signs or symptoms.
“Survival with breast cancer in this day and age is very good,” he says.

This content appeared in San Diego Health, a publication in partnership between Scripps and San Diego Magazine that celebrates the healthy spirit of San Diego.