Also known as: Infection - esophagus and Esophageal infection
- Leukemia or lymphoma
- Medicines that suppress the immune system, such as ones given after organ or bone marrow transplant
- Other conditions that suppress or weaken your immune system
- Candida albicans
- Cytomegalovirus (CMV)
- Herpes simplex virus (HSV)
- Human papillomavirus (HPV)
- Tuberculosis bacteria
- Difficulty swallowing and painful swallowing
- Fever and chills
- Yeast infection of the tongue and lining of the mouth (oral thrush)
- Sores in the mouth or back of the throat (with herpes or CMV)
- Blood and urine tests for CMV
- Culture of cells from the esophagus for herpes or CMV
- Mouth or throat swab culture for candida
- Antiviral medicines such as acyclovir, famciclovir, or valacyclovir can treat a herpes infection.
- Antifungal medicines such as fluconazole (taken by mouth), caspofungin (given by injection), or amphotericin (given by injection) can treat candida infection.
- Antiviral medicines that are given through a vein (intravenously), such as ganciclovir or foscarnet can treat CMV infection. In some cases, a medicine called valganciclovir, which is taken by mouth, can be used for CMV infection.
- Holes in your esophagus (perforations)
- Infection at other sites
- Recurrent infection
Esophagitis is a general term for any inflammation, irritation, or swelling of the esophagus. This is the tube that carries food and liquids from the mouth to the stomach.
Infectious esophagitis is rare. It often occurs in people whose immune systems are weakened. People who have strong immune systems don't usually develop the infection.
Common causes of a weakened immune system include:
Organisms (germs) that cause esophagitis include fungi, yeast, and viruses. Common organisms include:
Symptoms of esophagitis include:
Exams and Tests
The health care provider will ask about your symptoms and examine your mouth and throat. Tests may include:
You may need to have an upper endoscopy exam. This is a test to examine the lining of the esophagus.
In most people with esophagitis, medicines can control the infection. These include:
Some people may also need pain medicine.
Ask your provider for special diet recommendations. For example, there may be foods you need to avoid eating as your esophagitis heals.
Many people who are treated for an episode of infectious esophagitis need other, long-term medicines to suppress the virus or fungus, and to prevent the infection from coming back.
Esophagitis can usually be treated effectively and usually heals in 3 to 5 days. People with a weakened immune system may take longer to get better.
Health problems that may result from infectious esophagitis include:
When to Contact a Medical Professional
Call your provider if you have any condition that can cause reduced immune response and you develop symptoms of infectious esophagitis.
If you have a weakened immune system, try to avoid contact with people who have an infection with any of the organisms mentioned above.
Graman PS. Esophagitis. In: Bennett JE, Dolin R, Blaser MJ, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 8th ed. Philadelphia, PA: Elsevier Saunders; 2015:chap 99.
Katzka DA. Esophageal disorders caused by medications, trauma, and infection. In: Feldman M, Friedman LS, Brandt LJ, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology/Diagnosis/Management. 10th ed. Philadelphia, PA: Elsevier Saunders; 2016:chap 46.
- Review date:
- October 09, 2015
- Reviewed by:
- Jatin M. Vyas, MD, PhD, Assistant Professor in Medicine, Harvard Medical School; Assistant in Medicine, Division of Infectious Disease, Department of Medicine, Massachusetts General Hospital, Boston, MA. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. A licensed medical professional should be consulted for diagnosis and treatment of any and all medical conditions. Call 911 for all medical emergencies. Links to other sites are provided for information only -- they do not constitute endorsements of those other sites. © 1997- 2008 A.D.A.M., Inc. Any duplication or distribution of the information contained herein is strictly prohibited.