Conditions Treated

Types of cancers treated with radiation therapy

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Types of cancers treated with radiation therapy

A variety of radiation therapy options can be used to treat different types of benign and malignant tumors (cancer) as well as arteriovenous malformations (AVMs) and trigeminal neuralgia.


Depending on the cancer type, the location of the cancer and a patient’s medical history, radiation therapy may be:


  • Delivered as a first course of treatment
  • Delivered concurrently with treatments such as chemotherapy, immunotherapy or hormonal therapy
  • Delivered after treatments such as chemotherapy, immunotherapy, hormonal therapy or surgery

The type of radiation therapy recommended for specific cancers can vary, based on medical opinions of physicians and treatment teams. Radiation modalities has been commonly used for conditions and cancers, including:


Brain and central nervous system tumors and conditions

Including cancers, arteriovenous malformations (AVMs) and trigeminal neuralgia


  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Stereotactic radiosurgery (SRS) which includes Linac-based SRS, Gamma Knife (frame-based SRS), and CyberKnife (robotic frameless SRS)
  • Stereotactic body radiation therapy (SBRT)/stereotactic ablative radiotherapy (SABR)
  • Brachytherapy

Breast cancer

  • 3-D conformal radiation therapy including prone breast treatment
  • Intensity modulated radiation therapy (IMRT)
  • Intraoperative electron beam radiation therapy (IOERT)
  • AccuBoost, a non-invasive form of accelerated breast partial irradiation (APBI)
  • Hypofractionated whole breast radiation
  • Brachytherapy (such as SAVI, a catheter-based form of APBI)

Gastrointestinal and hepatobiliary cancers

Esophageal cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Brachytherapy high-dose rate (HDR)

Gallbladder and bile duct cancers

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Stereotactic body radiation therapy (SBRT)
  • CyberKnife (robotic SBRT with real-time tumor tracking)
  • Brachytherapy high-dose rate (HDR)

Gastric (stomach) cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Stereotactic body radiation therapy (SBRT)
  • CyberKnife (robotic SBRT with real-time tumor tracking)

Liver cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Stereotactic body radiation therapy (SBRT)
  • CyberKnife (robotic SBRT with real-time tumor tracking)

Pancreatic cancer

  • 3-D conformal radiation therapy
  • Intensity modulated radiation therapy (IMRT)
  • Stereotactic body radiation therapy (SBRT)
  • CyberKnife (robotic SBRT with real-time tumor tracking)

Anal cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy

Colon cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Brachytherapy

Rectal cancer

  • 3-D conformal radiation therapy
  • Intensity modulated radiation therapy (IMRT)
  • Intraoperative electron radiation therapy (IOERT)

Gastrointestinal carcinoid tumors

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy

Endocrine & neuroendocrine cancers

Pituitary tumors

  • Intensity modulated radiation therapy (IMRT)
  • Stereotactic radiosurgery (SRS)
  • Stereotactic body radiation therapy (SBRT)

Thyroid cancer

  • Systemic radiation therapy (iodine)
  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy

Genitourinary cancers

Bladder cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy

Kidney (renal) cancer

  • Intensity modulated radiation therapy (IMRT)
  • Stereotactic body radiation therapy (SBRT)
  • CyberKnife (robotic SBRT with real-time tumor tracking)

Penile cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Brachytherapy

Prostate cancer

  • Intensity modulated radiation therapy (IMRT)
  • Stereotactic body radiation therapy (SBRT), including Linac-based SBRT and CyberKnife (robotic SBRT with real-time tumor tracking)

Testicular cancer

  • 3-D conformal radiation therapy

Urethral cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Brachytherapy

Gynecologic cancers

Cervical cancer

  • 3-D conformal radiation therapy
  • Intensity modulated radiation therapy (IMRT)
  • Brachytherapy

Uterine (endometrial) cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Brachytherapy

Uterine sarcoma

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Brachytherapy

Ovarian cancer (when it has spread to other parts of body)

  • Intensity modulated radiation therapy (IMRT)/Image guided radiation therapy (IGRT)
  • 3-D conformal radiation therapy

Vaginal cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Brachytherapy

Vulvar cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Brachytherapy

Laryngeal and hypopharyngeal cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy

Metastatic squamous neck cancer with occult primary

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy

Nasopharyngeal cancer

  • Intensity modulated radiation therapy (IMRT)

Oropharyngeal cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy

Salivary gland cancer

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Neutron therapy

Lung cancers

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Stereotactic body radiation therapy/stereotactic ablative radiotherapy (SBRT/SABR)
  • CyberKnife (robotic SBRT with real-time tumor tracking)
  • Brachytherapy

Skin cancers

Basal cell carcinoma

  • Electrons
  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Kilovoltage radiation therapy

Squamous cell carcinoma

  • Electrons
  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Kilovoltage radiation therapy

Melanoma (most often when it has metastasized)

  • Stereotactic radiosurgery (SRS) including Linac-based SRS and Gamma Knife (frame-based SRS) and CyberKnife (robotic frameless SRS)
  • 3-D conformal radiation therapy
  • CyberKnife (robotic SBRT with real-time tumor tracking)

Sarcoma and bone cancers

Desmoid tumors

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • CyberKnife (robotic SBRT with real-time tumor tracking)

Ewing sarcoma

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy

Osteosarcoma

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • CyberKnife (robotic SBRT with real-time tumor tracking)

Soft tissue sarcoma

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Brachytherapy
  • CyberKnife (robotic SBRT with real-time tumor tracking)

Leukemia

  • Total body irradiation (TBI)

Lymphomas

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Total body irradiation (TBI)

Recurrent tumors and cancers

  • Intensity modulated radiation therapy (IMRT)
  • Stereotactic body radiation therapy (SBRT)
  • CyberKnife (robotic SBRT with real-time tumor tracking)

Metastatic cancers

  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy
  • Stereotactic body radiation therapy (SBRT)
  • CyberKnife (robotic SBRT with real-time tumor tracking)
  • Stereotactic radiosurgery (SRS) which includes Linac-based SRS, Gamma Knife (frame-based SRS), and CyberKnife (robotic frameless SRS)

Pediatric cancers

Through partnership with Rady Children’s Hospital San Diego.


  • Intensity modulated radiation therapy (IMRT)
  • 3-D conformal radiation therapy