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Active Studies

COVID-19 update:

In response to the COVID pandemic, Scripps Health has temporarily suspended enrollment for all clinical trials. Exceptions will exist for trials with curative intent, life-saving treatment or when no standard of care exists. For questions, please call Scripps Office for the Protection of Research Subjects at 858-678-6402.

Showing 21-30 results of 38 total
Cardiology and Vascular Diseases

INvesTigation to OptimizE Hemodynamic Management of HeartMate II™ Left VentricuLar Assist DEvice Patients using the CardioMEMS™ Pulmonary ArTery Pressure Sensor in Advanced Heart Failure (INTELLECT 2-HF)

This trial is not currently enrolling
This observational post market study is intended to characterize hemodynamic-guided management of patients with an existing left ventricular...
Cardiology and Vascular Diseases

COAPT Continued Access Study (CAS)

This trial is not currently enrolling
The purpose of the Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients with Functional Mitral...
Cardiology and Vascular Diseases

A Pilot Study of Edoxaban in Patients with Non-Valvular Atrial Fibrillation and Left Atrial Appendage Closure

This trial is not currently enrolling
This is a single arm, open label, single site study assessing the feasibility of post-procedural edoxaban therapy in atrial fibrillation (AF)...
Cancer

A PHASE III, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER, RANDOMIZED STUDY OF PRACINOSTAT IN COMBINATION WITH AZACITIDINE IN PATIENTS =18 YEARS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA UNFIT FOR STANDARD INDUCTION CHEMOTHERAPY [Protocol: PRAN-16-52]

This trial is not currently enrolling
This is a Phase III, multicenter, double-blind, randomized study of pracinostat vs. placebo with azacitidine (AZA) as background therapy in...
Cancer

A Master Protocol of Phase 1/2 Studies of Nivolumab in Advanced NSCLC Using Nivolumab as Maintenance after Induction Chemotherapy or as First-line Treatment Alone or in Combination with Standard of Care Therapies (Protocol CA209370)

This trial is not currently enrolling
The purpose of this study is to determine whether nivolumab monotherapy or in combination with Standard of care (SOC) therapies will provide...
Cancer

A PHASE Ib STUDY OF THE SAFETY AND PHARMACOKINETICS OF ATEZOLIZUMAB (ANTI-PD-L1 ANTIBODY) ALONE OR IN COMBINATION WITH AN IMMUNOMODULATORY DRUG AND/OR DARATUMUMAB IN PATIENTS WITH MULTIPLE MYELOMA (RELAPSED/REFRACTORY AND POST-AUTOLOGOUS STEM CELL TRANSPLANTATION)

This trial is not currently enrolling
This multicenter, open-label, Phase I study will evaluate the safety, efficacy, and pharmacokinetics of atezolizumab alone or in combination...
Cardiology and Vascular Diseases

Stoke AF

This trial is not currently enrolling
The purpose of the Stroke AF study is to compare the incidence of atrial fibrillation (AF) through 12 months between continuous cardiac rhythm...
Cardiology and Vascular Diseases

A Prospective Study of the Biofreedom Biolimus A9 Drug Coated Stent in Patients at High Risk for Bleeding

This trial is not currently enrolling
This study aims to confirm non-inferiority of the BioFreedom™ Drug Coated Stent to the Gazelle™ Bare Metal Stent arm of the Leaders Free study...
Orthopedics

A Prospective Multicenter Study Evaluating the Clinical and Radiographic Outcomes of Thoracolumbar Spine Surgery When Comprehensive Sagittal Alignment Surgical Planning is Used

This trial is not currently enrolling
A comprehensive approach to the evaluation of alignment in spinal surgery patients - through preoperative planning, intraoperative assessment,...
Digestive and Bowel Disorders

A prospective, single arm, multi-center study evaluating the short-term clinical outcomes of ventral hernias treated with OviTex® reinforced bioscaffold (Protocol TB2016.01.01)

This trial is not currently enrolling
The study is designed to demonstrate that the use of OviTex® 1S material for a ventral hernia repair leads to the same or a lower percentage of...