Why Newborns Get a Vitamin K Shot and Eye Ointment at Birth

Routine newborn treatments reduce risk of early illness

A newborn after receiving vitamin K shot and eye ointment to prevent health issues in first few days, weeks, months of life.

Routine newborn treatments reduce risk of early illness

Key Takeaways

  • Newborns have low vitamin K levels, raising bleeding risk.
  • One shot prevents serious internal and brain bleeding.
  • Eye ointment protects against infections during delivery.
  • Both treatments are safe and protect babies before their natural defenses develop.














Welcoming a new baby is a joyful and memorable moment, and it also comes with a few important steps to help keep your baby healthy. Soon after birth, most newborns receive two routine treatments: a vitamin K shot and antibiotic eye ointment.


Pediatricians recommend both because they help prevent rare but potentially serious conditions during a baby’s first days and months of life.


“Both of these well-established treatments give newborns important protection at a time when their bodies are still building natural defenses,” says Scarlett Chen, MD, a pediatrician at Scripps Clinic Rancho Bernardo.

Why Vitamin K Is important for newborns

Vitamin K helps the body form blood clots and stop bleeding. However, newborn babies are born with very low levels of this nutrient for several reasons:


  • Only small amounts pass from mother to baby during pregnancy
  • Newborns do not yet have gut bacteria that produce vitamin K
  • Breast milk contains low levels of vitamin K


Because of this, babies are more vulnerable to bleeding in the first weeks and months of life.

Understanding vitamin K deficiency bleeding

Low vitamin K levels can lead to vitamin K deficiency bleeding, also known as hemorrhagic disease of the newborn.


This condition can range from mild to severe. Symptoms include easy bruising, bleeding from the nose or mouth and oozing from the umbilical cord. In some cases, there may also be blood in the stool or urine.


Serious cases may cause internal bleeding, including in the brain, which can lead to brain damage, death or long-term developmental issues.


“This is one of those conditions where a baby can seem healthy, and then serious bleeding happens without warning. That is why prevention is so important,” Dr. Chen says.


Vitamin K deficiency bleeding is classified into three types:


  • Early: Occurs within the first 24 hours after birth
  • Classic: Occurs between days 2 and 7
  • Late: Occurs from 1 week to 6 months of age


Late cases are especially dangerous because they often involve bleeding in the brain and can occur in otherwise healthy infants. Babies who do not receive the vitamin K shot at birth are more than 80 times more likely to develop this serious bleeding.

How the vitamin K shot protects your baby

To help prevent bleeding, newborns get a one-time vitamin K shot within a few hours of birth. The injection is given in the baby’s thigh and provides reliable, long-lasting protection.


This is not just a short-term measure. The shot supports healthy blood clotting during the first months of life. Babies are most at risk then because their vitamin K levels are still low. Without this protection, even minor bleeding can quickly become serious.

Why newborns get antibiotic eye ointment

Most newborns also receive an antibiotic eye ointment, usually erythromycin, soon after birth. This treatment, called eye prophylaxis or infection prevention, helps protect against ophthalmia neonatorum, a serious eye infection that can be passed to a baby during delivery.


“Even when a parent has no symptoms, bacteria can still be passed during birth, which is why this simple step is so important,” Dr. Chen says.


The ointment protects against bacterial infections, such as gonorrhea and chlamydia, which can be transmitted during birth.


If left untreated, these infections can lead to:


  • Redness and swelling
  • Thick eye discharge
  • Corneal damage
  • Permanent vision loss


Although screening during pregnancy helps reduce risk, this step still matters because some infections may go undetected before delivery.

Are these newborn treatments safe?

Yes. Both the vitamin K shot and antibiotic eye ointment have been used safely for decades and are recommended by the American Academy of Pediatrics and other major health organizations.


The vitamin K shot has been extensively studied and is highly effective at preventing life-threatening bleeding in newborns. Earlier concerns about a possible link to childhood cancer have been carefully reviewed, and current evidence does not support any connection.


Side effects are minimal and typically mild:


  • The vitamin K shot may cause brief discomfort or soreness at the injection site
  • Eye ointment may briefly blur vision or cause mild irritation, but it clears quickly without lasting effects


Serious complications from either treatment are rare. By contrast, the conditions they help prevent can cause lasting harm or be life-threatening.

What parents should know

It’s normal to have questions about your baby’s care, especially in the first few days. The vitamin K shot and eye ointment are the first steps in protecting your baby’s health from birth.


“From the first hours after birth through the first year of life, regular checkups, vaccine and preventive care all play an important role,” says Dr. Chen. “Together, they support healthy growth and development during this important stage.”


Choosing a pediatrician before your baby is born can help you feel prepared and supported from day one. Your pediatrician is a key partner on this journey. They guide you through well-baby visits, recommended vaccines like measles protection and developmental milestones. 


At Scripps, pediatricians provide high‑quality, compassionate care to nurture your baby’s health, growth and development from the start.